Clomiphene Citrate – Clomid, Serophene
If your basic infertility work-up indicates that you are not ovulating regularly or if you are ovulating very late or early in the cycle, your physician may suggest Clomiphene Citrate.
Indications for use: In women, Clomiphene is used to induce ovulation, to correct irregular ovulation, to help increase egg production, and to correct luteal phase deficiency.
Dosage: Clomiphene comes in 50-mg tablets. The usual starting dose is one tablet on day 3, 4, or 5 of your cycle, and for 5 days afterward. Ovulation usually occurs on cycle day 13 to 18. If you do not ovulate, your physician may increase the dose in increments in future cycles; the maximum dose is usually 200mg daily. The American Society for Reproductive Medicine (ASRM) recommends that clomiphene be prescribed for three to six cycles only.
Clomid treatment has some potential for adverse effects. Side effects are definite “cons” of clomiphene use. Adverse effects are seen in some, but not all women using the drug.
- Mood swings, psychological / emotional side effects
- Hot flashes
- Abdominal discomfort
- Visual disturbances
- Ovarian cyst formation
- Thinning of the uterine endometrial lining
- Reduced production of cervical mucous
Use of Clomid increases risks for twins and multiple pregnancy
- 92% single
- 7% twins
- 0.5% triplets
- Very rarely higher than triplets